SCHEMBL6560299

SCHEMBL6560299

C=CS(=O)(=O)CCCNC(=O)Nc1ccc2c(O)cc(S(=O)(=O)O)cc2c1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 6/20 0.65
CASP6 P55212 3/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
NT5E P21589 1/20 0.46
NSD2 O96028 2/20 0.43
DUSP3 P51452 2/20 0.43
PTPN5 P54829 2/20 0.43
PTPN11 Q06124 2/20 0.43
EPHX1 P07099 3/20 0.41
CASP7 P55210 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352919 0.96 PRMT1 (0.67) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL9449398 0.84 PRMT1 (0.63) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL6559621 0.81 APEX1 (0.49) PRMT1CASP6CTDSP1NT5E
SCHEMBL6079067 0.80 PRMT1 (1.00) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL29349608 0.80 PRMT1 (1.00) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL2679101 0.80 PRMT1 (1.00) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL6562266 0.77 NT5E (0.56) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL9349425 0.76 APEX1 (0.51) PRMT1NT5E
SCHEMBL8416221 0.75 PRMT1 (0.83) PRMT1CASP6CTDSP1SIRT1NT5E
SCHEMBL9818196 0.74 PRMT1 (0.72) PRMT1CASP6CTDSP1SIRT1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0548795-B1 Water-soluble reactive dyes, their manufacture and their use HOECHST AG (DE) 1997-07-09 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
US-5138041-A Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0471702-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. HOECHST AG (DE) 1992-02-26 EP disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
EP-0385426-A1 Water soluble reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed
EP-0374758-A1 Water soluble dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed