Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | CD81 | P60033 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152426 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL611079 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL4905385 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL4905394 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL18723739 | 1.00 | GRM2 (0.38) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL6152852 | 0.86 | GRM2 (0.39) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL13851453 | 0.86 | GRM2 (0.39) | GRM2GRM5GRM1CD81SLC6A12 | |
| SCHEMBL13333996 | 0.82 | CD81 (0.31) | CD81 | |
| SCHEMBL2818518 | 0.79 | ATM (0.35) | — | |
| SCHEMBL17317455 | 0.79 | ATM (0.48) | GRM2GRM5GRM1SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |