SCHEMBL6560432

SCHEMBL6560432

CC(C(=O)N1CCOCC1)N1CCC(NS(=O)(=O)c2cc3cc(Cl)ccc3s2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067813 1.00 F10 (1.00) F10
SCHEMBL4484927 1.00 F10 (1.00) F10
SCHEMBL21067483 0.93 F10 (1.00) F10
SCHEMBL4487093 0.93 F10 (1.00) F10
SCHEMBL5146110 0.92 F10 (0.84) F10
SCHEMBL5143199 0.92 F10 (0.84) F10
SCHEMBL5144967 0.92 F10 (0.84) F10
SCHEMBL5146142 0.92 F10 (0.84) F10
SCHEMBL4478893 0.88 F10 (1.00) F10
SCHEMBL5473483 0.88 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395606-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2004-03-10 EP disclosed
WO-2002100886-A1 PYRROLIDIN-2-ONE DERIVATIVES AS INHIBITORS OF FACTOR XA GLAXO GROUP LIMITED (GB) 2002-12-19 WO disclosed