Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.58 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.57 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561153 | 1.00 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561634 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560267 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560262 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561742 | 0.87 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6562537 | 0.87 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561738 | 0.87 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560357 | 0.85 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560353 | 0.85 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560245 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |