Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561222 | 1.00 | MAPK1 (0.35) | MAPK1SMN1; SMN2TDP1PTGS2SIGMAR1 | |
| SCHEMBL6561351 | 0.91 | MAPK1 (0.37) | MAPK1SMN1; SMN2TDP1PTGS2HRH3 | |
| SCHEMBL6561354 | 0.91 | MAPK1 (0.37) | MAPK1SMN1; SMN2TDP1PTGS2HRH3 | |
| SCHEMBL6561780 | 0.89 | MAPK1 (0.37) | MAPK1SMN1; SMN2TDP1PTGS2HRH3 | |
| SCHEMBL6561782 | 0.89 | MAPK1 (0.37) | MAPK1SMN1; SMN2TDP1PTGS2HRH3 | |
| SCHEMBL6561882 | 0.88 | MAPK1 (0.35) | MAPK1SMN1; SMN2TDP1PTGS2SIGMAR1 | |
| SCHEMBL6561885 | 0.88 | MAPK1 (0.35) | MAPK1SMN1; SMN2TDP1PTGS2SIGMAR1 | |
| SCHEMBL6561459 | 0.81 | MAPK1 (0.34) | MAPK1SMN1; SMN2TDP1SIGMAR1HRH3 | |
| SCHEMBL6561462 | 0.81 | MAPK1 (0.34) | MAPK1SMN1; SMN2TDP1SIGMAR1HRH3 | |
| SCHEMBL6560523 | 0.75 | HIF1A (0.48) | MAPK1SMN1; SMN2TDP1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120403-B1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6313339-B1 | Aryl and heteroarylcylopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS ASIA, INC. | 2001-11-06 | — | — | US | disclosed |
| EP-1120403-A2 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |