Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.61 |
| ▸ | PPARG | P37231 | 19/20 | 0.61 |
| ▸ | PPARD | Q03181 | 19/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561721 | 0.88 | PPARA (0.76) | PPARAPPARGPPARDNR1H2NR1H3 | |
| SCHEMBL6561777 | 0.88 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL2066214 | 0.86 | PPARG (0.77) | PPARAPPARGPPARDNR1H2NR1H3 | |
| SCHEMBL6559335 | 0.85 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL7042144 | 0.84 | PPARA (0.80) | PPARAPPARGPPARD | |
| SCHEMBL6561716 | 0.81 | PPARG (0.59) | PPARAPPARGPPARDNR1H2NR1H3 | |
| SCHEMBL6560061 | 0.81 | PPARG (0.63) | PPARAPPARGPPARDNR1H2NR1H3 | |
| SCHEMBL6559347 | 0.80 | PPARG (0.64) | PPARAPPARGPPARD | |
| SCHEMBL6560063 | 0.80 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL6559945 | 0.76 | PPARG (0.84) | PPARAPPARGPPARDNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | claimed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | claimed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | claimed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |