Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.51 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561613 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6562594 | 0.93 | ITGB1 (0.45) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6562587 | 0.93 | ITGB1 (0.45) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561614 | 0.92 | ITGB1 (0.43) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560380 | 0.90 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560388 | 0.90 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6560384 | 0.82 | ITGB1 (0.46) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561198 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6563245 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561202 | 0.79 | ITGB1 (0.51) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |