Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561205 | 1.00 | MAPK1 (0.40) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6561207 | 1.00 | MAPK1 (0.40) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6560533 | 0.93 | HIF1A (0.41) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6560537 | 0.93 | HIF1A (0.41) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6560523 | 0.90 | HIF1A (0.48) | MAPK1SMN1; SMN2TDP1HIF1AALDH1A1 | |
| SCHEMBL6227065 | 0.89 | MAPK1 (0.42) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6227068 | 0.89 | MAPK1 (0.42) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6227062 | 0.89 | MAPK1 (0.42) | MAPK1SMN1; SMN2TDP1SLC9A1HIF1A | |
| SCHEMBL6561189 | 0.89 | HIF1A (0.38) | MAPK1SMN1; SMN2TDP1HIF1AALDH1A1 | |
| SCHEMBL6561771 | 0.89 | HIF1A (0.38) | MAPK1SMN1; SMN2TDP1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1120403-B1 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1120403-A2 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |