Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885319 | 0.91 | ACACB (0.43) | ACACBF10PPARGHPGDEED | |
| Hydrochloric Acid SCHEMBL5886010 | 0.90 | ACACB (0.42) | ACACBF10PPARGHPGDEED | |
| SCHEMBL6563935 | 0.87 | ACACB (0.48) | ACACBPPARGHPGD | |
| SCHEMBL6561958 | 0.82 | ACACB (0.49) | ACACBF10HPGDKMT2AF2 | |
| SCHEMBL5885762 | 0.82 | ACACB (0.44) | ACACBF10HPGDEEDHTT | |
| SCHEMBL5885442 | 0.81 | F10 (0.39) | ACACBF10PPARGF2PRSS1 | |
| Hydrochloric Acid SCHEMBL5885862 | 0.81 | ACACB (0.43) | ACACBF10HPGDEEDTPSAB1 | |
| Hydrochloric Acid SCHEMBL5885730 | 0.81 | F10 (0.39) | ACACBF10PPARGF2PRSS1 | |
| SCHEMBL5885690 | 0.80 | ACACB (0.41) | ACACBF10HPGDEEDITGB3 | |
| SCHEMBL5886050 | 0.80 | ACACB (0.45) | ACACBPPARGHPGDEEDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |