Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216418 | 0.85 | BACE1 (0.49) | BACE1EGFRNPSR1RXFP1GPR35 | |
| SCHEMBL1014901 | 0.83 | BACE1 (0.63) | BACE1EGFRNPSR1RXFP1GPR35 | |
| SCHEMBL29953102 | 0.83 | BACE1 (0.63) | BACE1EGFRNPSR1RXFP1GPR35 | |
| SCHEMBL10831447 | 0.81 | BACE1 (0.61) | BACE1EGFRNPSR1RXFP1MAPT | |
| SCHEMBL14564095 | 0.79 | EGFR (0.65) | BACE1EGFRNPSR1RXFP1GPR35 | |
| SCHEMBL14468256 | 0.78 | BACE1 (0.38) | BACE1EGFRGPR35MAPTNPC1 | |
| SCHEMBL8653035 | 0.78 | TSHR (0.60) | NPSR1GPR35MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29880479 | 0.78 | MAPK1 (0.58) | BACE1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL16952297 | 0.78 | MAPK1 (0.58) | BACE1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL16951426 | 0.78 | ERN1 (0.45) | BACE1EGFRMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109492-A1 | PYRROLOPYRIDAZINE COMPOUNDS AS KINASE INHIBITORS | GOSSAMER BIOSERVICES, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2020148571-A1 | METHOD AND DEVICE FOR ACID- OR BASE CONCENTRATION MEASUREMENT | TOMKA IVAN (HU) | 2020-07-23 | — | — | WO | disclosed |
| EP-0996870-B1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | DU PONT (US) | 2004-03-24 | — | — | EP | disclosed |
| US-6319648-B1 | USED FOR IMAGING MATERIALS OF SEMICONDUCTOR DEVICE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-11-20 | — | — | US | disclosed |
| EP-0996870-A1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999004319-A1 | IMPROVED DISSOLUTION INHIBITION RESISTS FOR MICROLITHOGRAPHY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-28 | — | — | WO | disclosed |