SCHEMBL6562683

SCHEMBL6562683

Cc1cc(C2(c3ccc(Cl)c(C)c3)c3ccccc3-c3ccccc32)ccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.65
ESR2 Q92731 1/20 0.65
MAPT P10636 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
OPRK1 P41145 1/20 0.47
CHRM5 P08912 2/20 0.38
POLB P06746 2/20 0.38
XBP1 P17861 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20763932 0.86 ESR1 (0.60) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL30446197 0.85 ESR1 (0.73) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL8984548 0.85 ESR1 (0.73) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL7050050 0.81 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL29580239 0.81 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL27212622 0.81 ESR1 (0.55) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL14559305 0.79 ESR2 (0.56) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL283244 0.79 ESR1 (0.65) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL70957 0.79 ESR1 (1.00) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL29412612 0.79 ESR1 (0.65) ESR1ESR2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023243205-A1 METHODS FOR PRODUCING AROMATIC THIOETHER SULFONE POLYMER, COMPOSITION, AND MOLDED ARTICLE DIC株式会社 2023-12-21 WO disclosed
WO-2023243204-A1 AROMATIC THIOETHER SULFONE POLYMER, COMPOSITION, AND MOLDED ARTICLE, AND METHODS FOR PRODUCING SAME DIC株式会社 2023-12-21 WO disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed