Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892411 | 0.83 | TRPV1 (0.66) | TRPV1EPHX2NR1H4 | |
| SCHEMBL4892408 | 0.83 | TRPV1 (0.66) | TRPV1EPHX2NR1H4 | |
| SCHEMBL12567953 | 0.76 | EPHX2 (0.80) | TRPV1EPHX2NR1H4 | |
| SCHEMBL1268701 | 0.75 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL12619647 | 0.74 | EPHX2 (1.00) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5827254 | 0.73 | EPHX2 (0.74) | TRPV1EPHX2NR1H4 | |
| SCHEMBL5947360 | 0.73 | EPHX2 (0.74) | TRPV1EPHX2NR1H4 | |
| SCHEMBL4890382 | 0.73 | EPHX2 (0.53) | TRPV1EPHX2NR1H4 | |
| SCHEMBL4890385 | 0.73 | EPHX2 (0.53) | TRPV1EPHX2NR1H4 | |
| SCHEMBL7131937 | 0.72 | TRPV1 (0.60) | TRPV1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303483-A4 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2004-11-03 | — | — | EP | claimed |
| EP-1303483-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-04-23 | — | — | EP | claimed |
| WO-2002016318-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | claimed |
| EP-1303483-A4 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2004-11-03 | — | — | EP | disclosed |
| EP-1303483-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002016318-A1 | NOVEL THIOUREA DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |