Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544432 | 0.94 | CYP2A6 (0.58) | CYP1A2MAP4K4CYP2A6ESR2HTT | |
| SCHEMBL20955807 | 0.94 | CYP2A6 (0.58) | CYP1A2MAP4K4CYP2A6ESR2HTT | |
| SCHEMBL29935106 | 0.94 | CYP2A6 (0.58) | CYP1A2MAP4K4CYP2A6ESR2HTT | |
| SCHEMBL29778098 | 0.94 | CYP2A6 (0.58) | CYP1A2MAP4K4CYP2A6ESR2HTT | |
| SCHEMBL29028999 | 0.89 | CYP1A2 (0.58) | CYP1A2MAP4K4CYP2A6ESR2KDM4E | |
| SCHEMBL24780966 | 0.89 | CYP2A6 (0.54) | CYP1A2MAP4K4CYP2A6ESR2KDM4E | |
| SCHEMBL28976272 | 0.89 | CYP2A6 (0.54) | CYP1A2MAP4K4CYP2A6ESR2HTT | |
| SCHEMBL19785362 | 0.87 | ESR2 (0.56) | CYP1A2MAP4K4CYP2A6ESR2KDM4E | |
| SCHEMBL24999271 | 0.85 | CYP1A2 (0.65) | CYP1A2MAP4K4CYP2A6ESR2KDM4E | |
| SCHEMBL25246242 | 0.85 | CYP1A2 (0.65) | CYP1A2MAP4K4CYP2A6ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122746-B1 | Composition for film formation and insulating film | JSR CORP (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-6468589-B2 | A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING | JSR CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| US-20010012870-A1 | Composition for film formation and insulating film | JSR CORPORATION (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122746-A1 | Composition for film formation and insulating film | JSR Corporation (JP) | 2001-08-08 | — | — | EP | disclosed |