Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687600 | 0.87 | KDM4E (0.34) | KDM4EGLACYP2C19KMT2APTGER4 | |
| SCHEMBL10433150 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL31650514 | 0.74 | TSHR (0.46) | KDM4EGLACYP2C19KMT2AALDH1A1 | |
| SCHEMBL2574774 | 0.74 | TSHR (0.46) | KDM4EGLACYP2C19KMT2AALDH1A1 | |
| SCHEMBL27571552 | 0.72 | KMT2A (0.41) | KDM4EGLACYP2C19KMT2AALDH1A1 | |
| SCHEMBL6546506 | 0.72 | KMT2A (0.48) | KMT2AALDH1A1GAARAB9ATSHR | |
| SCHEMBL9847085 | 0.71 | CYP3A4 (0.43) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL1444351 | 0.71 | PRKCI (0.39) | KDM4EGLACYP2C19KMT2APTGER4 | |
| SCHEMBL5185580 | 0.71 | KDM4E (0.47) | KDM4EGLACYP2C19KMT2AALDH1A1 | |
| SCHEMBL1497919 | 0.70 | HDAC6 (0.58) | KDM4EKMT2APTGER4ALDH1A1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399780-A1 | METHOD FOR PURIFYING FREE-BASE P-PHENYLENEDIAMINE-TYPE PHOTOGRAPHIC COLOR DEVELOPERS | EASTMAN CHEMICAL COMPANY (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003003115-A1 | METHOD FOR PURIFYING FREE-BASE P-PHENYLENEDIAMINE-TYPE PHOTOGRAPHIC COLOR DEVELOPERS | EASTMAN CHEMICAL COMPANY (US) | 2003-01-09 | — | — | WO | disclosed |