SCHEMBL6563418

SCHEMBL6563418

Cc1cc(CC(C)c2cc(C)c(O)c(C(C)(C)C)c2)cc(C(C)(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.47
CYP2C9 P11712 3/20 0.47
CYP2C19 P33261 3/20 0.47
HMGCR P04035 2/20 0.43
ALDH1A1 P00352 6/20 0.40
TSHR P16473 3/20 0.40
LMNA P02545 2/20 0.40
CYP2D6 P10635 2/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 3/20 0.39
HIF1A Q16665 3/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 2/20 0.39
BLM P54132 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GMNN O75496 1/20 0.39
GABBR2 O75899 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284104 0.89 HMGCR (0.53) CYP1A2CYP2C9CYP2C19HMGCRALDH1A1
SCHEMBL1581241 0.83 ESR1 (0.44) CYP1A2CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL12626206 0.82 CYP2C9 (0.52) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL9722727 0.82 CYP1A2 (0.45) CYP1A2CYP2C9CYP2C19HMGCRALDH1A1
SCHEMBL4378001 0.79 CYP2C9 (0.49) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL27075785 0.79 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19HMGCRALDH1A1
SCHEMBL21873723 0.79 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19HMGCRALDH1A1
SCHEMBL9777449 0.78 CYP2C9 (0.47) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL1151101 0.78 CYP2C9 (0.59) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL4450533 0.78 CYP2C9 (0.59) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680349-B2 POLYMER MATRIX HAVING A POLAR SIDE CHAIN AND A DAMPING IMPROVER OF BASIC NITROGEN AND A PHENOL-BASED COMPOUND MASAO SUMITA (JP) 2004-01-20 US claimed
EP-1186630-B1 Organohybrid-based damping material containing a damping improver and production method MASAO SUMITA (JP) 2004-02-04 EP disclosed
US-20030119958-A1 Organohybrid-based damping material, method for producing the same, and method for damping using the same MASAO SUMITA 2003-06-26 US disclosed
US-6566431-B1 For use in electric appliances, machines, chemistry, construction/civil engineering, and transportation Sumita, Masao (JP) 2003-05-20 US disclosed
US-20020049267-A1 Organohybrid-based damping material, method for producing the same, and damping improver for damping material SUMITA, MASAO (JP) 2002-04-25 US disclosed
EP-1186630-A1 Organohybrid-based damping material containing a damping improver and production method Masao Sumita (JP) 2002-03-13 EP disclosed