Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885236 | 0.90 | F10 (0.44) | F10PRSS1HPGDTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL5885871 | 0.89 | F10 (0.44) | F10PRSS1HPGDTSHRKMT2A | |
| SCHEMBL7671074 | 0.89 | F10 (0.43) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6563617 | 0.86 | PIK3CA (0.37) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6561958 | 0.86 | ACACB (0.49) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6563839 | 0.86 | PLAU (0.39) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6563410 | 0.85 | GAA (0.40) | F10PRSS1F2HPGDTSHR | |
| SCHEMBL6561938 | 0.82 | ABL1 (0.36) | F10HPGDTSHRL3MBTL3L3MBTL1 | |
| SCHEMBL6561829 | 0.81 | F2 (0.40) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7672248 | 0.81 | F2 (0.40) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |