Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885873 | 0.88 | ACACB (0.57) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL5885712 | 0.85 | ACACB (0.54) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL5885715 | 0.82 | ACACB (0.59) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL11998367 | 0.80 | ACACB (0.55) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL5885709 | 0.80 | ACACB (0.60) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL6556808 | 0.79 | ACACB (0.53) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL256029 | 0.79 | ACACB (0.53) | ACACBHPGDHTTTSHRGAA | |
| SCHEMBL6563806 | 0.79 | ACACB (0.52) | ACACBHPGDHTTKMT2AMEN1 | |
| SCHEMBL6563697 | 0.77 | ACACB (0.50) | ACACBHPGDHTTKMT2AL3MBTL1 | |
| SCHEMBL6563935 | 0.77 | ACACB (0.48) | ACACBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |