SCHEMBL6563888

SCHEMBL6563888

[O]C(=O)COc1ccc2ccccc2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 1/20 0.73
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65
PPARG P37231 3/20 0.65
NCOA2 Q15596 3/20 0.65
NCOA1 Q15788 3/20 0.65
NCOA3 Q9Y6Q9 3/20 0.65
HTT P42858 2/20 0.65
NPSR1 Q6W5P4 2/20 0.65
NR2E3 Q9Y5X4 1/20 0.65
NCOR2 Q9Y618 1/20 0.65
RAB9A P51151 3/20 0.61
HPGD P15428 2/20 0.59
NPC1 O15118 1/20 0.59
POLB P06746 3/20 0.58
GALR3 O60755 1/20 0.55
LMNA P02545 1/20 0.55
STAT3 P40763 1/20 0.55
AGXT P21549 2/20 0.55
TDP1 Q9NUW8 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27194588 0.86 PTPN7 (0.76) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL25640 0.85 PTPN7 (1.00) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL29367022 0.85 PTPN7 (1.00) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL4135864 0.83 PTPN7 (0.71) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL15201762 0.83 PTPN7 (0.96) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL1478177 0.83 PTPN7 (0.71) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL1725156 0.83 PTPN7 (0.71) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL30439679 0.83 PTPN7 (0.71) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL15201765 0.83 PTPN7 (0.96) PTPN7MEN1KMT2APPARGNCOA2
SCHEMBL29893936 0.81 PTPN7 (0.69) PTPN7MEN1KMT2APPARGNCOA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1085009-B1 INDAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2004-11-10 EP disclosed
EP-0934296-B1 CHROMAN DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2003-06-04 EP disclosed
US-6486178-B1 Indane derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-26 US disclosed
EP-1085009-A1 INDAN DERIVATIVES Nissan Chemical Industries, Ltd. (JP) 2001-03-21 EP disclosed
US-6066631-A Chroman derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-05-23 US disclosed
WO-2000012492-A1 BENZOXAZINE DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-09 WO disclosed
EP-0934296-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-08-11 EP disclosed
WO-1998004542-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-05 WO disclosed