Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.66 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4587057 | 0.99 | CXCR2 (0.65) | CXCR2CX3CR1MEN1KMT2ACXCR1 | |
| Hydrochloric Acid SCHEMBL7508535 | 0.89 | CXCR2 (0.54) | CXCR2CX3CR1MEN1KMT2ACXCR1 | |
| SCHEMBL4587185 | 0.88 | CXCR2 (0.73) | CXCR2CX3CR1 | |
| SCHEMBL6566439 | 0.88 | CXCR2 (0.70) | CXCR2CX3CR1MEN1KMT2ACXCR1 | |
| SCHEMBL6565712 | 0.87 | CXCR2 (0.68) | CXCR2CX3CR1CXCR1 | |
| Hydrochloric Acid SCHEMBL4587782 | 0.87 | CXCR2 (0.69) | CXCR2CX3CR1MEN1KMT2ACXCR1 | |
| SCHEMBL6566318 | 0.86 | CXCR2 (0.69) | CXCR2CX3CR1CXCR1 | |
| SCHEMBL4586753 | 0.86 | CXCR2 (0.77) | CXCR2CX3CR1 | |
| SCHEMBL4588491 | 0.85 | CXCR2 (0.69) | CXCR2CX3CR1 | |
| SCHEMBL5437226 | 0.85 | CXCR2 (0.65) | CXCR2CX3CR1CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161232-B1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-03-24 | — | — | EP | claimed |