Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 8/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SOX18 | P35713 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL656458 | 1.00 | PDPK1 (1.00) | PDPK1CYP1A2FFAR1SOX18HDAC1 | |
| SCHEMBL656456 | 1.00 | PDPK1 (1.00) | PDPK1CYP1A2FFAR1SOX18HDAC1 | |
| SCHEMBL659544 | 0.93 | PDPK1 (0.86) | PDPK1CYP1A2FFAR1HDAC1HDAC8 | |
| SCHEMBL659542 | 0.93 | PDPK1 (0.86) | PDPK1CYP1A2FFAR1HDAC1HDAC8 | |
| SCHEMBL659543 | 0.93 | PDPK1 (0.86) | PDPK1CYP1A2FFAR1HDAC1HDAC8 | |
| SCHEMBL659760 | 0.87 | PDPK1 (0.76) | PDPK1CYP1A2FFAR1SOX18HCAR2 | |
| SCHEMBL659761 | 0.87 | PDPK1 (0.76) | PDPK1CYP1A2FFAR1SOX18HCAR2 | |
| SCHEMBL659762 | 0.87 | PDPK1 (0.76) | PDPK1CYP1A2FFAR1SOX18HCAR2 | |
| SCHEMBL658624 | 0.83 | PDPK1 (0.71) | PDPK1CYP1A2FFAR1 | |
| SCHEMBL658626 | 0.83 | PDPK1 (0.71) | PDPK1CYP1A2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936608-B1 | REPROGRAMMING CELLS | SCRIPPS RESEARCH INST (US) | 2025-05-07 | — | — | EP | claimed |
| EP-3936608-A1 | REPROGRAMMING CELLS | The Scripps Research Institute (US) | 2022-01-12 | — | — | EP | claimed |
| EP-3199623-B1 | REPROGRAMMING CELLS | SCRIPPS RESEARCH INST (US) | 2021-07-28 | — | — | EP | claimed |
| CN-105176930-B | Reprogramming cells | 斯克里普斯研究所 | 2021-05-04 | — | — | CN | claimed |
| US-20210095257-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-04-01 | — | — | US | claimed |
| US-10738281-B2 | Reprogramming cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-08-11 | — | — | US | claimed |
| US-20190203182-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2019-07-04 | — | — | US | claimed |
| US-20170283776-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2017-10-05 | — | — | US | claimed |
| EP-3199623-A1 | REPROGRAMMING CELLS | The Scripps Research Institute (US) | 2017-08-02 | — | — | EP | claimed |
| US-9657274-B2 | Reprogramming cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-05-23 | — | — | US | claimed |
| US-9315779-B2 | Reprogramming cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-19 | — | — | US | claimed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | claimed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | claimed |
| US-20130323833-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2013-12-05 | — | — | US | claimed |
| EP-2553086-A1 | REPROGRAMMING CELLS | The Scripps Research Institute (US) | 2013-02-06 | — | — | EP | claimed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | claimed |
| WO-2011123572-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-06 | — | — | WO | claimed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | claimed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | claimed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | PDPK1 109/4885CYP1A2 4611/4885FFAR1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.