Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448218 | 0.81 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL9596832 | 0.81 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL9596827 | 0.81 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL16212189 | 0.80 | MAPK1 (0.45) | LMNACYP2C9AKR1C3TSHRAKR1C2 | |
| SCHEMBL1178318 | 0.80 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL2919840 | 0.80 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL1649474 | 0.80 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL9340076 | 0.77 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL8791404 | 0.77 | PTGS1 (0.53) | PTGS1PTGS2CXCR1CXCR2ALOX5 | |
| SCHEMBL9336469 | 0.77 | PTGS1 (0.59) | PTGS1PTGS2CXCR1CXCR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401432-A2 | IMIDAZOLE DERIVATIVES FOR MODULATING SODIUM CHANNELS | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102375-A2 | IMIDAZOLE DERIVATIVES FOR MODULATING SODIUM CHANNELS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.) (FR) | 2002-12-27 | — | — | WO | disclosed |