Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716977 | 0.84 | TSHR (0.31) | TSHR | |
| SCHEMBL7159046 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL7606636 | 0.79 | CYP2C19 (0.31) | TSHR | |
| SCHEMBL28595210 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL14707183 | 0.78 | TSHR (0.52) | TSHR | |
| SCHEMBL26719880 | 0.78 | TSHR (0.46) | TSHR | |
| SCHEMBL8528537 | 0.74 | — | — | |
| SCHEMBL17994854 | 0.74 | — | — | |
| SCHEMBL112219 | 0.74 | HMGCR (0.31) | TSHR | |
| SCHEMBL13389339 | 0.73 | TSHR (0.53) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020203397-A1 | AQUEOUS COATING COMPOSITION AND METHOD FOR FORMING MULTILAYERED COATING FILM | 関西ペイント株式会社 | 2020-10-08 | — | — | WO | disclosed |
| EP-0835891-B1 | Water-dispersible blocked isocyanate composition, and water-base paint composition and water base adhesive composition using the same | NIPPON POLYURETHANE KOGYO KK (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6080812-A | TRIMERIZING A DIISOCYANATE-DIOL-DIISOCYANATE CONDENSATION PRODUCT TO FORM ISOCYANURATE MACROMOLECULAR MONOMER, REACTING WITH HYDROPHILIC SURFACTANT TO FORM A URETHANE/ISOCYANURATE COPOLYMER, THEN BLOCKING REMAINING ISOCYANATE GROUPS | NIPPON POLYURETHANE INDUSTRY C. LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| US-5998539-A | ISOCYANATE BLOCKED WITH AN ALCOHOL | NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0835891-A1 | Water-dispersible blocked isocyanate composition, and water-base paint composition and water base adhesive composition using the same | Nippon Polyurethane Industry Co. Ltd. (JP) | 1998-04-15 | — | — | EP | disclosed |
| EP-0410167-A1 | Method of producing 2,2,-dimethyl-3-hydroxypropyl-2,2-dimethyl-3-hydroxypropionate | BASF Corporation (US) | 1991-01-30 | — | — | EP | disclosed |
| EP-0284679-A1 | Polysiloxane graft copolymers, flexible coating compositions comprising same and branched polysiloxane macromers for preparing same | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |