Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | F2 | P00734 | 8/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | PLAT | P00750 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034349 | 0.87 | F10 (0.46) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6749865 | 0.82 | F10 (0.51) | F10PRSS1F2 | |
| SCHEMBL6752283 | 0.82 | F10 (0.52) | F10PRSS1F2 | |
| SCHEMBL6749876 | 0.81 | F10 (0.50) | F10PRSS1F2 | |
| SCHEMBL7090138 | 0.80 | F10 (0.49) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7090541 | 0.80 | F10 (0.47) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6750749 | 0.80 | F10 (0.59) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7099152 | 0.80 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6564612 | 0.79 | F10 (0.55) | F10PRSS1F2 | |
| SCHEMBL7098603 | 0.79 | F10 (0.47) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |