Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | USP5 | P45974 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799563 | 0.84 | MEN1 (0.39) | KMT2AMEN1HTTGAAL3MBTL1 | |
| SCHEMBL26607361 | 0.82 | MEN1 (0.38) | KMT2AMEN1HTTGPR27HPGD | |
| SCHEMBL28267059 | 0.80 | MEN1 (0.37) | KMT2AMEN1HTTGPR27CYP1A2 | |
| SCHEMBL3863307 | 0.77 | HTT (0.62) | KMT2AMEN1HTTUSP5L3MBTL1 | |
| SCHEMBL11739448 | 0.77 | KMT2A (0.58) | KMT2AMEN1HTTUSP5L3MBTL1 | |
| SCHEMBL2796102 | 0.77 | HSD17B10 (0.44) | GAAGPR27HPGDHSD17B10ALDH1A1 | |
| SCHEMBL11620648 | 0.75 | MEN1 (0.38) | KMT2AMEN1HTTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7670687 | 0.75 | HSD17B10 (0.42) | KMT2AMEN1GAAGPR27HPGD | |
| SCHEMBL3519350 | 0.73 | KMT2A (0.74) | KMT2AMEN1HTTUSP5GAA | |
| SCHEMBL11014882 | 0.73 | KMT2A (0.54) | KMT2AMEN1HTTNPSR1USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |