Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.55 |
| ▸ | F2 | P00734 | 6/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
| ▸ | F9 | P00740 | 1/20 | 0.49 |
| ▸ | PROC | P04070 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238878 | 0.86 | F10 (0.57) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6839520 | 0.84 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6838928 | 0.82 | F10 (0.55) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3833828 | 0.82 | F10 (0.53) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3830430 | 0.81 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4681061 | 0.78 | F10 (0.52) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4680762 | 0.77 | F10 (0.51) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6258631 | 0.76 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6838432 | 0.76 | F10 (0.48) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10143891 | 0.76 | F10 (0.64) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | claimed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | claimed |