Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.67 |
| ▸ | PPARG | P37231 | 14/20 | 0.67 |
| ▸ | RXRA | P19793 | 9/20 | 0.67 |
| ▸ | RXRB | P28702 | 8/20 | 0.67 |
| ▸ | RXRG | P48443 | 6/20 | 0.67 |
| ▸ | PPARD | Q03181 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | PTGES | O14684 | 4/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997716 | 0.81 | PPARA (0.67) | PPARAPPARGRXRARXRBRXRG | |
| Pirinixic Acid SCHEMBL29370056 | 0.81 | PPARA (1.00) | PPARAPPARGRXRARXRBRXRG | |
| Pirinixic Acid SCHEMBL293161 | 0.81 | PPARA (1.00) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL11833234 | 0.80 | PPARA (0.82) | PPARAPPARGRXRARXRBRXRG | |
| Pirinixic Acid SCHEMBL6563348 | 0.79 | PPARA (0.80) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL6563962 | 0.78 | PPARA (0.78) | PPARAPPARGRXRARXRBRXRG | |
| Acetic Acid SCHEMBL3773388 | 0.77 | PPARA (0.61) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL11483023 | 0.77 | PPARA (0.77) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL6565495 | 0.77 | PPARA (0.77) | PPARAPPARGRXRARXRBRXRG | |
| SCHEMBL11490882 | 0.77 | PPARA (0.63) | PPARAPPARGRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399426-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING BETA-AMYLOID PRODUCTION | Active Pass Pharmaceuticals, Inc. (CA) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100836-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING BETA-AMYLOID PRODUCTION | ACTIVE PASS PHARMACEUTICALS, INC. (CA) | 2002-12-19 | — | — | WO | disclosed |