SCHEMBL6566209

SCHEMBL6566209

CCC(=CCCC(=O)O)c1ccc(COc2ccc(C(C)(C)O[SiH2]C(C)(C)C)c(C(C)(C)O[SiH2]C(C)(C)C)c2)s1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.34
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562933 0.87 MRGPRX4 (0.32) FFAR1MRGPRX4
SCHEMBL6566273 0.87
SCHEMBL6564820 0.87
SCHEMBL7610182 0.85
SCHEMBL6565073 0.84 POLB (0.36) POLBTDP1
SCHEMBL6564649 0.84
SCHEMBL6564671 0.84 MRGPRX4 (0.30) MRGPRX4
SCHEMBL6566220 0.82 POLB (0.37) FFAR1POLBTDP1MRGPRX4
SCHEMBL6566426 0.82 FFAR1 (0.31) FFAR1
SCHEMBL6562828 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235824-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-05-19 EP disclosed