Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696258 | 0.86 | PPARG (0.63) | PPARGCYP3A4 | |
| SCHEMBL4695219 | 0.85 | PPARG (0.44) | PPARG | |
| SCHEMBL6564341 | 0.81 | PPARG (0.58) | PPARGCYP3A4CCNCCDK8 | |
| SCHEMBL27482498 | 0.78 | BRD4 (0.49) | CYP3A4 | |
| SCHEMBL6565936 | 0.77 | PPARG (0.51) | PPARGCYP3A4 | |
| SCHEMBL6568150 | 0.77 | PPARG (0.58) | PPARGCYP3A4 | |
| SCHEMBL4696595 | 0.76 | PPARG (0.51) | PPARGCYP3A4 | |
| SCHEMBL4694703 | 0.76 | HPGD (0.46) | PPARG | |
| SCHEMBL2034696 | 0.76 | PPARG (0.50) | PPARGCYP3A4 | |
| SCHEMBL6567959 | 0.75 | PPARG (0.51) | PPARGCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | PPARG 802/4885CYP3A4 139/4885CCNC 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.