Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101654 | 0.88 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6100933 | 0.87 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6100605 | 0.87 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| Hydrochloric Acid SCHEMBL6099402 | 0.87 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6100336 | 0.85 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6100356 | 0.83 | KMT2A (0.56) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6098671 | 0.83 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6101129 | 0.83 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6099067 | 0.82 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2HTTKMT2ASTAT3 | |
| SCHEMBL6102164 | 0.82 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2HTTKMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |