Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | HTR1E | P28566 | 1/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567092 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| Hydrochloric Acid SCHEMBL6101760 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| Hydrochloric Acid SCHEMBL6101765 | 0.99 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6099523 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| Hydrochloric Acid SCHEMBL6100925 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6099785 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6099791 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6101654 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6098863 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTNPSR1TSHR | |
| SCHEMBL6100933 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAHTTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403235-A1 | N-ARYLPHENYLACETAMIDE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |