SCHEMBL6567172

SCHEMBL6567172

CCOc1ccc(C2(C3CCCCC3)CCCCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 4/20 0.49
SLC6A2 P23975 3/20 0.49
SLC6A3 Q01959 3/20 0.49
NQO1 P15559 1/20 0.44
ALDH1A1 P00352 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
KMT2A Q03164 3/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775622 0.76 FFAR1 (0.40) SLC6A4SLC6A2SLC6A3KMT2AMEN1
SCHEMBL9614557 0.76 PARP15 (0.40) SLC6A4SLC6A2SLC6A3HPGD
SCHEMBL18911113 0.73 HRH3 (0.57) NQO1ALDH1A1NPC1RAB9AKMT2A
SCHEMBL22500142 0.73 ESR2 (0.53) SLC6A4SLC6A2SLC6A3
SCHEMBL10511848 0.73 MAPT (0.38) SLC6A4SLC6A2SLC6A3ALDH1A1NPC1
SCHEMBL10634800 0.72 SLC6A4 (0.40) SLC6A4SLC6A2SLC6A3
SCHEMBL27852674 0.72 SLC6A4 (0.43) SLC6A4SLC6A2SLC6A3NPC1RAB9A
SCHEMBL27869454 0.72 SLC6A4 (0.43) SLC6A4SLC6A2SLC6A3ALDH1A1RAB9A
SCHEMBL58980 0.72 SLC6A2 (0.62) SLC6A4SLC6A2SLC6A3
SCHEMBL5681343 0.72 EPHX1 (0.45) SLC6A4SLC6A2SLC6A3ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0919536-B1 Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same DAINIPPON INK & CHEMICALS (JP) 2004-04-07 EP disclosed
US-6693223-B1 STRONG POLAR COMPOUND HAVING LARGE DIELECTRIC ANISOTROPY; EXERTS EXCELLENT THRESHOLD VOLTAGE REDUCING EFFECT; EXCELLENT MISCIBILITY WITH CONVENTIONAL LIQUID CRYSTAL MATERIALS DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-02-17 US disclosed
US-20020053659-A1 Fluorine-substituted-4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-05-09 US disclosed
US-6287646-B1 MIXTURES DAINIPPON INK AND CHEMICALS, INC. (JP) 2001-09-11 US disclosed
EP-0919536-A1 Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-06-02 EP disclosed