Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931115 | 0.76 | EPHX2 (1.00) | EPHX2MEN1NPC1LMNATP53 | |
| SCHEMBL12932214 | 0.75 | EPHX2 (0.90) | EPHX2 | |
| SCHEMBL12932434 | 0.75 | EPHX2 (1.00) | EPHX2MAPTHTT | |
| SCHEMBL12932148 | 0.74 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL4927703 | 0.74 | EPHX2 (0.77) | EPHX2MAPT | |
| SCHEMBL4266417 | 0.74 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL6566823 | 0.74 | CNR2 (0.52) | EPHX2MEN1NPC1LMNATP53 | |
| SCHEMBL4356291 | 0.74 | EPHX2 (0.72) | EPHX2MEN1NPC1LMNATP53 | |
| SCHEMBL4346744 | 0.74 | EPHX2 (1.00) | EPHX2MEN1NPC1LMNATP53 | |
| SCHEMBL4257580 | 0.73 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |