Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566881 | 0.86 | EPHX2 (0.72) | EPHX2MAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL4346744 | 0.82 | EPHX2 (1.00) | EPHX2MAPTLMNA | |
| SCHEMBL4113279 | 0.78 | EPHX2 (0.65) | EPHX2MAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL4348906 | 0.78 | EPHX2 (0.73) | EPHX2MAPTNPSR1LMNA | |
| SCHEMBL12932434 | 0.77 | EPHX2 (1.00) | EPHX2MAPTALDH1A1 | |
| SCHEMBL28399545 | 0.76 | MAPT (0.78) | EPHX2MAPTNPSR1LMNA | |
| SCHEMBL6649644 | 0.76 | EPHX2 (0.58) | EPHX2MAPTNPSR1ALDH1A1HPGD | |
| SCHEMBL11685462 | 0.76 | SMN1; SMN2 (0.63) | MAPTNPSR1ALDH1A1HPGDLMNA | |
| SCHEMBL11754054 | 0.76 | SMN1; SMN2 (0.63) | MAPTNPSR1ALDH1A1HPGDLMNA | |
| SCHEMBL15335335 | 0.76 | EPHX2 (1.00) | EPHX2MAPTNPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |