Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351106 | 0.84 | CNR1 (0.68) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL22834233 | 0.84 | KDM4E (0.71) | RAB9AMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL18317190 | 0.80 | NAMPT (0.62) | RAB9AMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL14433911 | 0.80 | KDR (0.59) | MEN1KMT2ANAMPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6568654 | 0.79 | CNR1 (0.60) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL14434575 | 0.79 | NAMPT (0.61) | RAB9AMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL3461023 | 0.79 | NAMPT (0.61) | RAB9AMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL6568451 | 0.77 | KDM4E (0.69) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL6566847 | 0.77 | CNR1 (0.71) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL4357505 | 0.77 | CNR1 (0.60) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |