Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657395 | 0.94 | SMN1; SMN2 (0.61) | CNR2CNR1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL31318741 | 0.86 | SMN1; SMN2 (0.54) | CNR2CNR1SMN1; SMN2MAPTTSHR | |
| SCHEMBL657957 | 0.84 | SMN1; SMN2 (0.66) | CNR2CNR1SMN1; SMN2L3MBTL1CYP4F2 | |
| SCHEMBL6228355 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL657249 | 0.81 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL657503 | 0.80 | SMN1; SMN2 (0.57) | CNR2SMN1; SMN2MAPTTSHRCYP3A4 | |
| SCHEMBL9484542 | 0.80 | CNR2 (0.52) | CNR2CNR1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL656591 | 0.80 | CNR2 (0.52) | CNR2CNR1SMN1; SMN2MAPTTSHR | |
| SCHEMBL703931 | 0.77 | MAPT (0.72) | MAPTL3MBTL1TSHRNPC1RAB9A | |
| SCHEMBL13534379 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTTSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | CNR2 4264/4885CNR1 4048/4885SMN1; SMN2 4389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.