Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603596 | 1.00 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL27679054 | 1.00 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29612319 | 1.00 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29357080 | 0.95 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL38945 | 0.95 | ESR1 (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11610619 | 0.94 | ESR1 (0.48) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28315152 | 0.89 | HSPA5 (0.43) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5405788 | 0.88 | HMGCR (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4830860 | 0.88 | HMGCR (0.47) | ESR1HMGCR | |
| SCHEMBL20942801 | 0.86 | ESR1 (0.47) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401941-A1 | STABILISED METALLOCENE POLYOLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002092684-A1 | STABILISED METALLOCENE POLYOLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | WO | disclosed |
| EP-0063544-A1 | Copolymers of alpha-olefines containing sterically hindered amino groups | CIBA-GEIGY AG (CH) | 1982-10-27 | — | — | EP | disclosed |