SCHEMBL6567403

SCHEMBL6567403

C=CC(=O)OC(CC)C/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3179521 0.81 TSHR (0.38) TSHRKDM4EHPGD
SCHEMBL3179507 0.81 TSHR (0.38) TSHRKDM4EHPGD
SCHEMBL611315 0.80 TSHR (0.34) TSHRKDM4E
SCHEMBL14973429 0.80 TSHR (0.34) TSHRKDM4E
SCHEMBL561301 0.77 TSHR (0.45) TSHRHPGD
Acrylic Acid SCHEMBL11036393 0.73 TSHR (0.42) TSHRHPGD
SCHEMBL19456905 0.73 TSHR (0.45) TSHRHPGD
SCHEMBL4410270 0.72 TSHR (0.35) TSHRHPGD
SCHEMBL3164711 0.72 TSHR (0.41) TSHRHPGD
SCHEMBL28636721 0.72 TSHR (0.51) TSHRKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399489-A1 METHOD FOR PRODUCING POLYMER COMPOSITIONS, POLYMER COMPOSITIONS OBTAINED BY USING THIS METHOD, AND THE USE THEREOF Rohmax Additives GmbH (DE) 2004-03-24 EP disclosed
WO-2002096959-A1 METHOD FOR PRODUCING POLYMER COMPOSITIONS, POLYMER COMPOSITIONS OBTAINED BY USING THIS METHOD, AND THE USE THEREOF ROHMAX ADDITIVES GMBH (DE) 2002-12-05 WO disclosed