SCHEMBL6567845

SCHEMBL6567845

CC(C)(C)C(Cc1ccc(O)cc1)(C(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.62
ESR1 P03372 6/20 0.61
ESR2 Q92731 5/20 0.50
CA2 P00918 3/20 0.45
CAMK2A Q9UQM7 1/20 0.45
SLC7A5 Q01650 1/20 0.43
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 2/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5360398 0.84 SMN1; SMN2 (0.53) BLMALDH1A1CYP3A4CYP1A2RECQL
SCHEMBL21269695 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL28314407 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL21269875 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL28314481 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL28315754 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL21269112 0.82 HIF1A (0.52) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL28314538 0.81 HIF1A (0.50) BLMALDH1A1CYP3A4MEN1KMT2A
SCHEMBL55626 0.81 BLM (0.62) BLMESR1ESR2CA2CAMK2A
SCHEMBL11596247 0.80 BLM (0.67) BLMESR1ESR2CA2CAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401941-A1 STABILISED METALLOCENE POLYOLEFINS BASF AKTIENGESELLSCHAFT (DE) 2004-03-31 EP disclosed
WO-2002092684-A1 STABILISED METALLOCENE POLYOLEFINS BASF AKTIENGESELLSCHAFT (DE) 2002-11-21 WO disclosed
EP-1181330-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2002-02-27 EP disclosed
WO-2000066661-A1 MIXTURES CONTAINING STABILISERS AND IMINOPHOSPHORANES BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO disclosed
EP-1027348-A1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 2000-08-16 EP disclosed
WO-1999023093-A1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-05-14 WO disclosed