Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.50 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664943 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL30028532 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL28576660 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL30681768 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL6037469 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL28583460 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL9627027 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL9627770 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL22115926 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB | |
| SCHEMBL30027900 | 1.00 | HMGCR (0.50) | HMGCRPTPN7SELPTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118235086-A | Radiation-sensitive composition comprising a combination of metals or metalloid compounds | 埃斯普投资有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-113636904-B | Green preparation method of conjugated diyne compound with participation of water-soluble vitamin E | 浙江工业大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-113636904-A | Green preparation method of conjugated diyne compound with participation of water-soluble vitamin E | 浙江工业大学 | 2021-11-12 | — | — | CN | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-5310959-A | Reacting 1-decyne with 1,4-dihalo-2-butyne using a strong base and then reacting with 5-hexynoic acid; reacting with an amine in the presense of carbonyldiimidazole to amidate | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1994-05-10 | — | — | US | disclosed |
| US-5066427-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES DITE CIRD (FR) | 1991-11-19 | — | — | US | disclosed |
| US-4877789-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES DITE C.I.R.D. (FR) | 1989-10-31 | — | — | US | disclosed |
| EP-0032622-B1 | POLYMERISABLE PHOSPHOLIPIDS AND POLYMERS THEREOF, METHODS FOR THEIR PREPARATION, METHODS FOR THEIR USE IN COATING SUBSTRATES AND FORMING LIPOSOMES AND THE RESULTING COATED SUBSTRATES AND LIPOSOME COMPOSITIONS | Chapman, Dennis (GB) | 1985-08-14 | — | — | EP | disclosed |
| US-4348329-A | PHOSPHOLIPIDS HAVING CONJUGATED DI-YNE SYSTEM | AVANTI POLAR LIPIDS, INC. | 1982-09-07 | — | — | US | disclosed |
| EP-0032622-A1 | Polymerisable phospholipids and polymers thereof, methods for their preparation, methods for their use in coating substrates and forming liposomes and the resulting coated substrates and liposome compositions | Chapman, Dennis (GB) | 1981-07-29 | — | — | EP | disclosed |