Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236526 | 0.96 | KMT2A (0.58) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL6249941 | 0.96 | KMT2A (0.58) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL6249937 | 0.96 | KMT2A (0.58) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL236527 | 0.96 | KMT2A (0.58) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL31499163 | 0.94 | NAALAD2 (0.58) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL3340707 | 0.94 | KMT2A (0.57) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL935547 | 0.94 | KMT2A (0.57) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL3340721 | 0.94 | KMT2A (0.57) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| Glycine SCHEMBL28484996 | 0.93 | KMT2A (0.53) | KMT2ANAALAD2CNR2MMP2MMP9 | |
| SCHEMBL20302075 | 0.88 | KMT2A (0.50) | KMT2ANAALAD2CNR2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171110-B1 | PHENYLACETIC ACID COMPOSITIONS FOR TREATING OR PREVENTING ATHEROSCLEROSIS AND RESTENOSIS | BURZYNSKI STANISLAW R (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1171110-A2 | PHENYLACETIC ACID COMPOSITIONS FOR TREATING OR PREVENTING ATHEROSCLEROSIS AND RESTENOSIS | Burzynski, Stanislaw R. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6127419-A | Phenylacetic acid compositions for treating or preventing atherosclerosis and restenosis | BURZYNSKI STANISLAW R (US) | 2000-10-03 | — | — | US | disclosed |
| WO-2000030627-A2 | PHENYLACETIC ACID COMPOSITIONS FOR TREATING OR PREVENTING ATHEROSCLEROSIS AND RESTENOSIS | BURZYNSKI STANISLAW R (US) | 2000-06-02 | — | — | WO | disclosed |