Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566999 | 0.86 | CASR (0.41) | NPY5RKMT2AROCK2ROCK1MEN1 | |
| SCHEMBL6565988 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL6566982 | 0.84 | MTOR (0.47) | KDM4EALDH1A1NPY5RKMT2AMEN1 | |
| SCHEMBL6564606 | 0.83 | CNR1 (0.58) | ALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL6564452 | 0.80 | KMT2A (0.56) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL6568022 | 0.79 | CASR (0.45) | KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6564738 | 0.78 | CASR (0.44) | KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL6568097 | 0.78 | CASR (0.54) | KDM4EALDH1A1ROCK2ROCK1 | |
| SCHEMBL6566741 | 0.76 | MEN1 (0.52) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL6565846 | 0.76 | MEN1 (0.52) | ALDH1A1POLBKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | KDM4E 2962/4885ALDH1A1 907/4885POLB 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.