Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.51 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.51 |
| ▸ | ITGAL | P20701 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308860 | 1.00 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6570042 | 0.86 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6317195 | 0.86 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL6308813 | 0.83 | ITGAL (0.39) | ITGB2ICAM1ITGAL | |
| SCHEMBL6308844 | 0.82 | S1PR1 (0.37) | ITGB2ICAM1ITGAL | |
| SCHEMBL6568600 | 0.79 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL6310429 | 0.79 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL7642569 | 0.78 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL6311224 | 0.78 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL6569923 | 0.78 | ITGB2 (0.62) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | claimed |
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |