Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567736 | 1.00 | DPP4 (0.52) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL6567731 | 1.00 | DPP4 (0.52) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL6568329 | 1.00 | DPP4 (0.52) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL21452231 | 0.86 | CDK4 (0.45) | DPP4HTR2AHTR2CHTR2BTP53 | |
| SCHEMBL29851647 | 0.86 | DPP4 (0.58) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL13598558 | 0.86 | DPP4 (0.58) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL18611826 | 0.82 | HTR2A (0.45) | DPP4HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL6567398 | 0.81 | CDK4 (0.48) | DPP4HTR2AHTR2CHTR2BTP53 | |
| SCHEMBL6567402 | 0.81 | CDK4 (0.48) | DPP4HTR2AHTR2CHTR2BTP53 | |
| SCHEMBL6567401 | 0.81 | CDK4 (0.48) | DPP4HTR2AHTR2CHTR2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280811-B1 | HYDROFORMYLATION METHOD, BRIDGED COMPOUNDS OF PHOSPHORUS, ARSENIC AND ANTIMONY AND CATALYST COMPRISING A COMPLEX OF SAID BRIDGED COMPOUNDS | BASF AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| EP-1280811-A1 | HYDROFORMYLATION METHOD, BRIDGED COMPOUNDS OF PHOSPHORUS, ARSENIC AND ANTIMONY AND CATALYST COMPRISING A COMPLEX OF SAID BRIDGED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001085739-A1 | HYDROFORMYLATION METHOD, BRIDGED COMPOUNDS OF PHOSPHORUS, ARSENIC AND ANTIMONY AND CATALYST COMPRISING A COMPLEX OF SAID BRIDGED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |