⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451083 | 0.77 | — | — | |
| SCHEMBL31390729 | 0.73 | — | — | |
| SCHEMBL5072847 | 0.68 | — | — | |
| SCHEMBL4496549 | 0.68 | — | — | |
| Benzene SCHEMBL7136089 | 0.67 | — | — | |
| SCHEMBL3950859 | 0.66 | — | — | |
| SCHEMBL2175787 | 0.66 | — | — | |
| SCHEMBL4849512 | 0.65 | — | — | |
| SCHEMBL28564504 | 0.65 | — | — | |
| SCHEMBL17097355 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478613-A2 | SUBSTITUTED 10-ARYL-11H-BENZO[B]FLUORENES AND 7-ARYL-5,6-DIHYDRO-BENZ[A]ANTHRACENES FOR SELECTIVE EFFECTS ON ESTROGEN RECEPTORS | Akzo Nobel N.V. (NL) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070675-A2 | SUBSTITUTED 10-ARYL-11H-BENZO[B]FLUORENES AND 7-ARYL-5,6-DIHYDRO-BENZO[A]ANTHRACENES FOR SELECTIVE EFFECTS ON ESTROGEN RECEPTORS | AKZO NOBEL N.V. (NL) | 2003-08-28 | — | — | WO | disclosed |
| US-20030144313-A1 | Non-steroidal, tetracylic compounds for estrogen-related treatments | N.V. ORGANON (NL) | 2003-07-31 | — | — | US | disclosed |