Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12932201 | 0.83 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL12932180 | 0.83 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL1420838 | 0.83 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL12932185 | 0.82 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL12932224 | 0.81 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL12932237 | 0.80 | EPHX2 (0.73) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL4007997 | 0.80 | EPHX2 (0.69) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL12932211 | 0.80 | EPHX2 (1.00) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL4003310 | 0.80 | EPHX2 (0.67) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL22002225 | 0.80 | EPHX2 (0.66) | EPHX2ALDH1A1MAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |