Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 18/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105151 | 0.82 | S1PR2 (0.57) | EPHX2HSD11B1 | |
| SCHEMBL4100429 | 0.81 | EPHX2 (0.61) | EPHX2 | |
| SCHEMBL4115718 | 0.79 | EPHX2 (0.68) | EPHX2HSD11B1P2RX7 | |
| SCHEMBL4113279 | 0.78 | EPHX2 (0.65) | EPHX2 | |
| SCHEMBL4109697 | 0.78 | EPHX2 (0.63) | EPHX2HSD11B1 | |
| SCHEMBL4115733 | 0.77 | EPHX2 (0.70) | EPHX2 | |
| SCHEMBL4115929 | 0.76 | EPHX2 (0.62) | EPHX2HSD11B1 | |
| SCHEMBL4107118 | 0.75 | EPHX2 (0.75) | EPHX2HSD11B1 | |
| SCHEMBL4121410 | 0.75 | EPHX2 (0.64) | EPHX2 | |
| SCHEMBL4101944 | 0.75 | EPHX2 (0.53) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |