Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29615207 | 0.85 | CNR1 (1.00) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22834241 | 0.85 | CNR1 (1.00) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6568654 | 0.81 | CNR1 (0.60) | CNR1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29615111 | 0.79 | CNR1 (0.82) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22834264 | 0.79 | CNR1 (0.82) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4351106 | 0.78 | CNR1 (0.68) | CNR1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13853577 | 0.78 | CA12 (0.69) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9781759 | 0.78 | CA12 (0.69) | CNR1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3054824 | 0.78 | MAPK1 (0.58) | CNR1POLBMEN1KMT2AMAPT | |
| SCHEMBL9051137 | 0.75 | CA1 (0.69) | MEN1KMT2ASMN1; SMN2MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |