SCHEMBL6568630

SCHEMBL6568630

O=C(O)c1ccc(Oc2ccc(C(C(F)(F)F)C(F)(F)F)cc2)cc1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.54
ALDH1A1 P00352 1/20 0.49
HPSE Q9Y251 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
APEX1 P27695 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
TDP1 Q9NUW8 5/20 0.43
LMNA P02545 1/20 0.43
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41
GRM4 Q14833 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29962773 1.00 POLB (0.54) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL8580061 0.87 POLB (0.50) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL8473883 0.84 POLB (0.57) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL2266320 0.82 POLB (0.61) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL1719563 0.82 HSD17B10 (0.55) POLBALDH1A1L3MBTL1TDP1CYP2C9
SCHEMBL30553345 0.82 POLB (0.73) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL29406842 0.82 POLB (0.73) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL30901880 0.82 POLB (0.73) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL145176 0.82 POLB (0.73) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL262311 0.82 POLB (0.73) POLBALDH1A1HPSEL3MBTL1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0875906-B1 Electronic part and process for manufacturing the same JSR CORP (JP) 2004-04-07 EP disclosed
US-6084053-A AS STRUCTURAL COMPONENT, A DIELECTRIC POLYIMIDE MATERIAL HAVING AT LEAST ONE FLUORENE-CONTAINING STRUCTURAL UNIT; APPLYING POLYIMIDE SOLUTION TO SUBSTRATE, AND DRYING TO FORM THE DIELECTRIC; HEAT RESISTANCE, LOW DIELECTRIC CONSTANT JSR CORPORATION (JP) 2000-07-04 US disclosed
EP-0875906-A2 Electronic part and process for manufacturing the same JSR Corporation (JP) 1998-11-04 EP disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed