Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.47 |
| ▸ | ITGAL | P20701 | 19/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817159 | 1.00 | ITGB2 (0.47) | ITGB2ICAM1ITGALMIF | |
| SCHEMBL6312904 | 0.82 | ITGB2 (0.52) | ITGB2ICAM1ITGAL | |
| SCHEMBL5195443 | 0.82 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL6568758 | 0.80 | MIF (0.44) | MIF | |
| SCHEMBL6567050 | 0.80 | CA1 (0.49) | MIF | |
| SCHEMBL6567044 | 0.80 | CA1 (0.49) | MIF | |
| SCHEMBL6310687 | 0.79 | ITGAL (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL5254352 | 0.76 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL5254346 | 0.76 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL7646849 | 0.76 | ITGB2 (0.74) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |