Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569276 | 1.00 | CYP11B1 (0.33) | CYP11B1CYP11B2DAOMAPTTP53 | |
| SCHEMBL6567179 | 0.90 | DAO (0.33) | CYP11B1CYP11B2DAOMAPTCACNA1H | |
| SCHEMBL6567183 | 0.90 | DAO (0.33) | CYP11B1CYP11B2DAOMAPTCACNA1H | |
| SCHEMBL6896414 | 0.88 | DAO (0.36) | DAOMAPTCACNA1HMEN1KMT2A | |
| SCHEMBL6896417 | 0.88 | DAO (0.36) | DAOMAPTCACNA1HMEN1KMT2A | |
| SCHEMBL6569179 | 0.87 | TP53 (0.40) | CYP11B1CYP11B2MAPTTP53THRB | |
| SCHEMBL6569172 | 0.87 | TP53 (0.40) | CYP11B1CYP11B2MAPTTP53THRB | |
| SCHEMBL12453678 | 0.87 | PTPN1 (0.39) | CYP11B1CYP11B2DAOMAPTTP53 | |
| SCHEMBL6898541 | 0.86 | PTPN1 (0.33) | — | |
| SCHEMBL6569177 | 0.86 | PTPN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919536-B1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK & CHEMICALS (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6693223-B1 | STRONG POLAR COMPOUND HAVING LARGE DIELECTRIC ANISOTROPY; EXERTS EXCELLENT THRESHOLD VOLTAGE REDUCING EFFECT; EXCELLENT MISCIBILITY WITH CONVENTIONAL LIQUID CRYSTAL MATERIALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-02-17 | — | — | US | disclosed |
| US-20020053659-A1 | Fluorine-substituted-4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-05-09 | — | — | US | disclosed |
| US-6287646-B1 | MIXTURES | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0919536-A1 | Fluorine-substituted 4-alkenylbenzoic acid and derivatives thereof, and nematic liquid crystal composition containing cyanophenyl benzoate derivatives and liquid crystal display system using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-06-02 | — | — | EP | disclosed |